VCOTTVanderbilt Collaborative for Obesity Trials and Translational science

Publications

Publications by the co-directors of VCOTT, the Vanderbilt Collaborative for Obesity Trials and Translational science, drawn automatically from their ORCID records.

The list reflects each co-director's published work and is not limited to studies conducted through VCOTT.

2026

  1. Samuels JM, Williams CR, Patel MB, Self WH, Funk LM, Roumie C, et al. GLP-1 Receptor Agonists Post-Bariatric Surgery (GRABS) Trial: Rationale, Design and Baseline Characteristics. Diabetes, Obesity and Metabolism, 2026.
    doi:10.1111/dom.71320
  2. Chen Y, Piantek G, Zhang X, Feng Y, Yan C, Samuels JM, et al. Patient-Reported Continuity of GLP-1 Receptor Agonist Therapy. Obesity Science & Practice, 2026.
    doi:10.1002/osp4.70189
  3. Northup CJ, Albaugh VL, Clapp B, Hollenbeak CS, Peterson RM, Morton JM, et al. The American Society of Metabolic and Bariatric Surgery 2022-2024 procedural volume assessment. Surgery for Obesity and Related Diseases, 2026.
    doi:10.1016/j.soard.2026.09.018
  4. Samuels JM, Holler E, Spann MD, Northup CJ, Yuce TK. Prevalence of Pre-Clinical Obesity Among US Adults Receiving Medical and Surgical Obesity Treatment. Obesity, 2026.
    doi:10.1002/oby.70171
  5. Chao AM, Walsh S, Rama PR, Samuels JM. Obesity Treatment Pathways and Implementation in Health Systems. Obesity Science & Practice, 2026.
    doi:10.1002/osp4.70142
  6. Wang Z, Zheng Y, Wang L, Flynn CR, Shu XO, Cai Q, et al. Obesity-Related Metabolites are Associated with Incident Coronary Heart Disease and Respond to Metabolic and Bariatric Surgery. 2026. Preprint.
    doi:10.64898/2026.03.06.26347826
  7. Zheng Y, Guo Z, Jeong E, Xu S, Samuels JM, Dawwas GK, et al. Weight loss from glucagon-like peptide-1 receptor agonists by genetic factors in adults with type 2 diabetes. Diabetes Research and Clinical Practice, 2026.
    doi:10.1016/j.diabres.2025.113041
  8. Wang Z, Wang L, Zhang X, Lowery BD, Shaffer LL, Chen Y, et al. Body Composition Changes After Bariatric Surgery or Treatment With GLP-1 Receptor Agonists. JAMA Network Open, 2026.
    doi:10.1001/jamanetworkopen.2025.53323
  9. Holler E, Samuels JM, Stefanidis D, Yuce TK. Preoperative GLP-1 Receptor Agonist Use and Weight Loss Outcomes Following Bariatric Surgery. Annals of Surgery, 2026.
    doi:10.1097/sla.0000000000007042

2025

  1. Samuels JM, Ye F, Irlmeier R, Silver H, Srivastava G, Spann M. Real-world titration, persistence & weight loss of semaglutide and tirzepatide in an academic obesity clinic. Diabetes, Obesity and Metabolism, 2025.
    doi:10.1111/dom.70004
  2. Dawwas GK, Samuels JM, Stein CM. Shifting obesity treatment paradigms: Trends of glucagon-like peptide-1 receptor agonists and bariatric surgery in the United States. Diabetes, Obesity and Metabolism, 2025.
    doi:10.1111/dom.16600
  3. Wang L, Zhang X, Chen Y, Flynn CR, English WJ, Samuels JM, et al. Reduced Risk of Cardiovascular Diseases After Bariatric Surgery Based on the New Predicting Risk of Cardiovascular Disease EVENTs Equations. Journal of the American Heart Association, 2025.
    doi:10.1161/jaha.124.038191
  4. Samuels JM, Patel MB, Roumie CL, Self W, Funk L, Spann MD, et al. Patients experience with preoperative use of anti-obesity medications and associations with bariatric surgery expectations. Surgery for Obesity and Related Diseases, 2025.
    doi:10.1016/j.soard.2024.08.041
  5. Cheung-Flynn J, Rathmacher JA, Pitchford LM, Xiong Y, Flynn CR. Reactive Dicarbonyl Scavenging with 2-Hydroxybenzylamine Improves MASH. Nutrients, 2025.
    doi:10.3390/nu17040610
  6. Chen Y, Feng Y, Zhang X, Gifford KA, Elmanzalawi Y, Samuels J, et al. Bariatric Surgery Is Associated With Reduced Incidence of Mild Cognitive Impairment and Alzheimer Disease and Related Dementias: A Retrospective Cohort Study. Annals of Surgery Open, 2025.
    doi:10.1097/as9.0000000000000541
  7. Samuels JM, English W, Birdwell KA, Feurer ID, Shaffer D, Geevarghese SK, et al. Medical and Surgical Weight Loss as a Pathway to Renal Transplant Listing. The American Surgeon™, 2025.
    doi:10.1177/00031348241275714
  8. Yuan W, Xu S, Dionisi S, von Herrmann K, Frederick-Dyer K, Cheung-Flynn J, et al. Physiological foundation modeling for subclinical disease assessment: a prospective pilot. medRxiv, 2025.
    doi:10.1101/2025.08.20.25334090
  9. Resistance training, but not leucine, increased basal muscle protein synthesis and reversed frailty in older women consuming optimized protein intake. GEROSCIENCE, 2025.
    doi:10.1007/s11357-025-01877-2
  10. Habashy A, Acree C, Kim KY, Zahraei A, Dufresne M, Phan S, et al. Spatial patterns of hepatocyte glucose flux revealed by stable isotope tracing and multi-scale microscopy. Nature Communications, 2025.
    doi:10.1038/s41467-025-60994-w
  11. Nikolla E, Grandberry A, Jamerson D, Flynn CR, Sundaresan S. The Enteric Neuronal Circuitry: A Key Ignored Player in Nutrient Sensing Along the Gut-Brain Axis. The FASEB Journal, 2025.
    doi:10.1096/fj.202500220rr
  12. Chatterjee E, Betti MJ, Sheng Q, Lin P, Emont MP, Li G, et al. The extracellular vesicle transcriptome provides tissue-specific functional genomic annotation relevant to disease susceptibility in obesity. Cell Genomics, 2025.
    doi:10.1016/j.xgen.2025.100925
  13. Steinhauser S, Estoppey D, Buehler DP, Xiong Y, Pizzato N, Rietsch A, et al. The transcription factor ZNF469 regulates collagen production in liver fibrosis. JCI Insight, 2025.
    doi:10.1172/jci.insight.182232
  14. Albaugh VL, Weinberg JL, Yu D, Spann MD, Williams DB, Samuels JM, et al. Total Alimentary Limb Length Is Not Associated with Weight Loss Following Proximal Roux-en-Y Gastric Bypass. Obesity Surgery, 2025.
    doi:10.1007/s11695-025-07817-5

2024

  1. Zhang X, Kang K, Yan C, Feng Y, Vandekar S, Yu D, et al. Association Between Patient Portal Engagement and Weight Loss Outcomes in Patients After Bariatric Surgery: Longitudinal Observational Study Using Electronic Health Records. Journal of Medical Internet Research, 2024.
    doi:10.2196/56573 PubMed 39652378
  2. Samuels JM, Niswender KD, Roumie CL, Spann MD, Flynn CR, Ye F, et al. Adverse event comparison between glucagon-like peptide-1 receptor agonists and other antiobesity medications following bariatric surgery. Diabetes, Obesity and Metabolism, 2024.
    doi:10.1111/dom.15737
  3. Wang L, O’Brien MT, Zhang X, Chen Y, English WJ, Williams B, et al. Cardiometabolic Improvements After Metabolic Surgery and Related Presurgery Factors. Journal of the Endocrine Society, 2024.
    doi:10.1210/jendso/bvae027 PubMed 38487212
  4. Chiusa M, Lee YA, Zhang MZ, Harris RC, Sherrill T, Lindner V, et al. Cytoplasmic retention of the DNA/RNA-binding protein FUS ameliorates organ fibrosis in mice. Journal of Clinical Investigation, 2024.
    doi:10.1172/jci175158 PubMed 38488009
  5. Samuels JM, Paddu NU, Rekulapeli A, Madhar A, Srivastava G. High Prevalence of Positive Genetic Obesity Variants in Postoperative Bariatric Surgery Patients with Weight Regain Presenting for Medical Obesity Intervention. Obesity Surgery, 2024.
    doi:10.1007/s11695-023-06952-1
  6. Pope R, English W, Walden R, Bradley E, Spann M, Ardila-Gatas J, et al. Non-Operative Approach to Contained Perforated Marginal Ulcers: A Systematic Review and Case Series. American Surgeon, 2024.
    doi:10.1177/00031348231209533
  7. Samuels JM, Albaugh VL, Yu D, Chen Y, Williams DB, Spann MD, et al. Sex- and operation-dependent effects on 5-year weight loss results of bariatric surgery. Surgery for Obesity and Related Diseases, 2024.
    doi:10.1016/j.soard.2024.01.013
  8. Samuels JM, Patel MB, Niswender KD. Time to Rethink the Approach to Treating Obesity. JAMA Surgery, 2024.
    doi:10.1001/jamasurg.2024.1502

2023

  1. Samuels J, Carmichael H, Hazel K, Velopulos C, Rothchild K, Schoen J. Chronic psychiatric diagnoses increase emergency department utilization following bariatric surgery. Surgical Endoscopy, 2023.
    doi:10.1007/s00464-022-09451-z
  2. Rathmacher JA, Fuller JC, Abumrad NN, Flynn CR. Inflammation Biomarker Response to Oral 2-Hydroxybenzylamine (2-HOBA) Acetate in Healthy Humans. Inflammation, 2023.
    doi:10.1007/s10753-023-01801-w PubMed 36935449
  3. Jacobse J, Brown RE, Li J, Pilat JM, Pham L, Short SP, et al. Interleukin-23 receptor signaling impairs the stability and function of colonic regulatory T cells. Cell Reports, 2023.
    doi:10.1016/j.celrep.2023.112128 PubMed 36807140
  4. Sundaresan S, Johnson C, Dixon KB, Dole M, Kilkelly D, Antoun J, et al. Intraduodenal nutrient infusion differentially alters intestinal nutrient sensing, appetite, and satiety responses in lean and obese subjects. The American Journal of Clinical Nutrition, 2023.
    doi:10.1016/j.ajcnut.2023.06.011 PubMed 37661107
  5. Ukita R, Wu WK, Liang J, Talackine JR, Patel YJ, Francois SA, et al. Pulmonary artery banding in sheep: a novel large animal model for congestive hepatopathy. Journal of Applied Physiology, 2023.
    doi:10.1152/japplphysiol.00473.2022 PubMed 36759164
  6. Swei E, Helmkamp L, Samuels J, Schoen J, Scott FI, Wani S, et al. Reflux and Barrett's esophagus after sleeve gastrectomy: analysis of a statewide database. Surgery for Obesity and Related Diseases, 2023.
    doi:10.1016/j.soard.2023.02.008
  7. Samuels JM, Yachimski P, Gamboa A, Spann M, Ardila-Gatas J. Use of lumen-apposing metal stents in treating gastrojejunal anastomotic strictures in bariatric patients. Surgical Endoscopy, 2023.
    doi:10.1007/s00464-023-10117-7

Drawn from ORCID; each entry links to its DOI or PubMed record where one is recorded. ORCID records: Jason M. Samuels; Charles Robert Flynn. Retrieved November 9, 2026.